4-Chloro-2-nitro-1-(trifluoromethoxy)benzene structure

4-Chloro-2-nitro-1-(trifluoromethoxy)benzene

TL;DR: 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene (CAS 448-38-4) is a chemical compound with molecular formula C7H3ClF3NO3 and molecular weight 240.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-chloro-2-nitro-1-(trifluoromethoxy)benzene

Also Known As: 4-chloro-2-nitro-1-(trifluoromethoxy)benzene, 5-CHLORO-2-(TRIFLUOROMETHOXY)NITROBENZENE, 3-Nitro-4-(trifluoromethoxy)chlorobenzene, 4-chloro-2-nitro-1-trifluoromethoxybenzene, 4-chloro-2-nitro-1-trifluoromethoxy-benzene

CAS: 448-38-4
Molecular Formula C7H3ClF3NO3
Molecular Weight 240.98 g/mol
LogP 3.1468
Topological Polar Surface Area 52.37 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 240.97536
Heavy Atoms 15
Complexity 393.55707

Chemical Identifiers

CAS Number 448-38-4
SMILES C1=CC(=C(C=C1Cl)[N+](=O)[O-])OC(F)(F)F

Product Overview

4-Chloro-2-nitro-1-(trifluoromethoxy)benzene (CAS 448-38-4), with molecular formula C7H3ClF3NO3 and molecular weight 240.98 g/mol. IUPAC: 4-chloro-2-nitro-1-(trifluoromethoxy)benzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene

XLogP
3.1468
TPSA (Topological Polar Surface Area)
52.37
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
15
Complexity
393.55707
Exact Mass
240.97536
Monoisotopic Mass
240.97536
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene

The XLogP value of 3.1468 indicates that 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.37 Ų, 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene?

The CAS number of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene is 448-38-4.

What is the molecular formula of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene?

The molecular formula of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene is C7H3ClF3NO3.

What is the molecular weight of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene?

The molecular weight of 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene is 240.98 g/mol.

Where can I buy 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene?

You can request a quote for 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene?

Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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