RepSox structure

RepSox

TL;DR: RepSox (CAS 446859-33-2) is a chemical compound with molecular formula C17H13N5 and molecular weight 287.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[5-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine

Also Known As: RepSox, ALK5 Inhibitor II, ALK5 Inhibitor, 1vjy, RepSox (GMP)

CAS: 446859-33-2
Molecular Formula C17H13N5
Molecular Weight 287.12 g/mol
LogP 2.2
Topological Polar Surface Area 67.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 287.1171
Heavy Atoms 22
Complexity 376.0

Chemical Identifiers

CAS Number 446859-33-2
SMILES CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
InChIKey LBPKYPYHDKKRFS-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Biotechnology (2 patents)

Product Overview

RepSox (CAS 446859-33-2), with molecular formula C17H13N5 and molecular weight 287.12 g/mol. IUPAC: 2-[5-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RepSox

XLogP
2.2
TPSA (Topological Polar Surface Area)
67.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
22
Complexity
376.0
Exact Mass
287.1171
Monoisotopic Mass
287.1171
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RepSox

The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RepSox. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for RepSox. Following Lipinski's Rule of Five, RepSox has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RepSox?

The CAS number of RepSox is 446859-33-2.

What is the molecular formula of RepSox?

The molecular formula of RepSox is C17H13N5.

What is the molecular weight of RepSox?

The molecular weight of RepSox is 287.12 g/mol.

Where can I buy RepSox?

You can request a quote for RepSox directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RepSox?

Yes, KEHONG BIO provides custom synthesis services for RepSox and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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