Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide structure

Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide

TL;DR: Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide (CAS 446831-87-4) is a chemical compound with molecular formula C13H13NO4S2 and molecular weight 311.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(5-ethylsulfonyl-2-hydroxyphenyl)thiophene-2-carboxamide

Also Known As: ChemDiv2_000263, BAS 00567977, Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide, N-(5-ethylsulfonyl-2-hydroxyphenyl)thiophene-2-carboxamide, N-[5-(ethylsulfonyl)-2-hydroxyphenyl]-2-thienylcarboxamide

CAS: 446831-87-4
Molecular Formula C13H13NO4S2
Molecular Weight 311.03 g/mol
LogP 2.0
Topological Polar Surface Area 120.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 311.0286
Heavy Atoms 20
Complexity 446.0

Chemical Identifiers

CAS Number 446831-87-4
SMILES CCS(=O)(=O)C1=CC(=C(C=C1)O)NC(=O)C2=CC=CS2
InChIKey XLOZXTUDRBCWES-UHFFFAOYSA-N

Product Overview

Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide (CAS 446831-87-4), with molecular formula C13H13NO4S2 and molecular weight 311.03 g/mol. IUPAC: N-(5-ethylsulfonyl-2-hydroxyphenyl)thiophene-2-carboxamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide

XLogP
2.0
TPSA (Topological Polar Surface Area)
120.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
20
Complexity
446.0
Exact Mass
311.0286
Monoisotopic Mass
311.0286
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide

The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide. Following Lipinski's Rule of Five, Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide?

The CAS number of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide is 446831-87-4.

What is the molecular formula of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide?

The molecular formula of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide is C13H13NO4S2.

What is the molecular weight of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide?

The molecular weight of Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide is 311.03 g/mol.

Where can I buy Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide?

You can request a quote for Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide?

Yes, KEHONG BIO provides custom synthesis services for Thiophene-2-carboxylic acid (5-ethanesulfonyl-2-hydroxy-phenyl)-amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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