![4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/446/446278-12-2.png)
4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one (CAS 446278-12-2) is a chemical compound with molecular formula C28H23ClN2O4S and molecular weight 518.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione
Also Known As: 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one, (4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]pyrrolidine-2,3-dione, (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione, 4-(4-chlorobenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(6-methoxybenzo[d]thiazol-2-yl)-1H-pyrrol-2(5H)-one
| Molecular Formula | C28H23ClN2O4S |
|---|---|
| Molecular Weight | 518.11 g/mol |
| LogP | 6.708 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 518.1067 |
| Heavy Atoms | 36 |
| Complexity | 1507.1018 |
Chemical Identifiers
| CAS Number | 446278-12-2 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2/C(=C(/C3=CC=C(C=C3)Cl)\O)/C(=O)C(=O)N2C4=NC5=C(S4)C=C(C=C5)OC |
Product Overview
4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one (CAS 446278-12-2), with molecular formula C28H23ClN2O4S and molecular weight 518.11 g/mol. IUPAC: (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 6.708 indicates that 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one is 446278-12-2.
What is the molecular formula of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one is C28H23ClN2O4S.
What is the molecular weight of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one is 518.11 g/mol.
Where can I buy 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-[(4-chlorophenyl)carbonyl]-3-hydroxy-1-(6-methoxy-1,3-benzothiazol-2-yl)-5-[4-(propan-2-yl)phenyl]-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.