4-Methyl-alpha-(trifluoromethyl)benzenemethanol structure

4-Methyl-alpha-(trifluoromethyl)benzenemethanol

TL;DR: 4-Methyl-alpha-(trifluoromethyl)benzenemethanol (CAS 446-65-1) is a chemical compound with molecular formula C9H9F3O and molecular weight 190.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2,2,2-trifluoro-1-(4-methylphenyl)ethanol

Also Known As: 2,2,2-Trifluoro-1-(p-tolyl)ethanol, 2,2,2-trifluoro-1-p-tolylethanol, 2,2,2-trifluoro-1-(4-methylphenyl)ethanol, 2,2,2-trifluoro-1-p-tolyl-ethanol, alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol

CAS: 446-65-1
Molecular Formula C9H9F3O
Molecular Weight 190.06 g/mol
LogP 2.5
Topological Polar Surface Area 20.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 190.06055
Heavy Atoms 13
Complexity 159.0

Chemical Identifiers

CAS Number 446-65-1
SMILES CC1=CC=C(C=C1)C(C(F)(F)F)O
InChIKey LNYGOJDJKXEXDR-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (13 patents) Organic Building Blocks (9 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

4-Methyl-alpha-(trifluoromethyl)benzenemethanol (CAS 446-65-1), with molecular formula C9H9F3O and molecular weight 190.06 g/mol. IUPAC: 2,2,2-trifluoro-1-(4-methylphenyl)ethanol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol

XLogP
2.5
TPSA (Topological Polar Surface Area)
20.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
13
Complexity
159.0
Exact Mass
190.06055
Monoisotopic Mass
190.06055
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol

The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Methyl-alpha-(trifluoromethyl)benzenemethanol. With a topological polar surface area (TPSA) of 20.2 Ų, 4-Methyl-alpha-(trifluoromethyl)benzenemethanol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Methyl-alpha-(trifluoromethyl)benzenemethanol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol?

The CAS number of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol is 446-65-1.

What is the molecular formula of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol?

The molecular formula of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol is C9H9F3O.

What is the molecular weight of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol?

The molecular weight of 4-Methyl-alpha-(trifluoromethyl)benzenemethanol is 190.06 g/mol.

Where can I buy 4-Methyl-alpha-(trifluoromethyl)benzenemethanol?

You can request a quote for 4-Methyl-alpha-(trifluoromethyl)benzenemethanol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Methyl-alpha-(trifluoromethyl)benzenemethanol?

Yes, KEHONG BIO provides custom synthesis services for 4-Methyl-alpha-(trifluoromethyl)benzenemethanol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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