BAS 06899789 structure

BAS 06899789

TL;DR: BAS 06899789 (CAS 445462-63-5) is a chemical compound with molecular formula C21H19F2N5 and molecular weight 379.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,8aR)-6-amino-8-(2,4-difluorophenyl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

Also Known As: BAS 06899789, 6-amino-8-(2,4-difluorophenyl)-2-propyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile, AM-807/12740218, (8R,8aR)-6-amino-8-(2,4-difluorophenyl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile, (8R,8aR)-6-amino-8-(2,4-difluorophenyl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile

CAS: 445462-63-5
Molecular Formula C21H19F2N5
Molecular Weight 379.16 g/mol
LogP 3.10014
Topological Polar Surface Area 100.63 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 379.16086
Heavy Atoms 28
Complexity 975.51904

Chemical Identifiers

CAS Number 445462-63-5
SMILES CCCN1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=C(C=C(C=C3)F)F

Product Overview

BAS 06899789 (CAS 445462-63-5), with molecular formula C21H19F2N5 and molecular weight 379.16 g/mol. IUPAC: (8R,8aR)-6-amino-8-(2,4-difluorophenyl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of BAS 06899789

XLogP
3.10014
TPSA (Topological Polar Surface Area)
100.63
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
28
Complexity
975.51904
Exact Mass
379.16086
Monoisotopic Mass
379.16086
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of BAS 06899789

The XLogP value of 3.10014 indicates that BAS 06899789 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 100.63 Ų falls within the moderate polarity range, balancing permeability and solubility for BAS 06899789. Following Lipinski's Rule of Five, BAS 06899789 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of BAS 06899789?

The CAS number of BAS 06899789 is 445462-63-5.

What is the molecular formula of BAS 06899789?

The molecular formula of BAS 06899789 is C21H19F2N5.

What is the molecular weight of BAS 06899789?

The molecular weight of BAS 06899789 is 379.16 g/mol.

Where can I buy BAS 06899789?

You can request a quote for BAS 06899789 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for BAS 06899789?

Yes, KEHONG BIO provides custom synthesis services for BAS 06899789 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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