AN-648/41078465 structure

AN-648/41078465

TL;DR: AN-648/41078465 (CAS 445429-60-7) is a chemical compound with molecular formula C21H19N3O4S and molecular weight 409.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 4-methyl-2-[(4E)-3-methyl-5-oxo-4-[(4-prop-2-ynoxyphenyl)methylidene]pyrazol-1-yl]-1,3-thiazole-5-carboxylate

Also Known As: AN-648/41078465, (E)-ethyl 4-methyl-2-(3-methyl-5-oxo-4-(4-(prop-2-yn-1-yloxy)benzylidene)-4,5-dihydro-1H-pyrazol-1-yl)thiazole-5-carboxylate, 4-Methyl-2-{3-methyl-5-oxo-4-[1-(4-prop-2-ynyloxy-phenyl)-meth-(E)-ylidene]-4,5-dihydro-pyrazol-1-yl}-thiazole-5-carboxylic acid ethyl ester, ethyl 4-methyl-2-[(4E)-3-methyl-5-oxo-4-[(4-prop-2-ynoxyphenyl)methylidene]pyrazol-1-yl]-1,3-thiazole-5-carboxylate, ethyl 4-methyl-2-{(4E)-3-methyl-5-oxo-4-[4-(prop-2-yn-1-yloxy)benzylidene]-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazole-5-carboxylate

CAS: 445429-60-7
Molecular Formula C21H19N3O4S
Molecular Weight 409.11 g/mol
LogP 3.44632
Topological Polar Surface Area 81.09 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 409.10962
Heavy Atoms 29
Complexity 1044.8688

Chemical Identifiers

CAS Number 445429-60-7
SMILES CCOC(=O)C1=C(N=C(S1)N2C(=O)/C(=C/C3=CC=C(C=C3)OCC#C)/C(=N2)C)C

Product Overview

AN-648/41078465 (CAS 445429-60-7), with molecular formula C21H19N3O4S and molecular weight 409.11 g/mol. IUPAC: ethyl 4-methyl-2-[(4E)-3-methyl-5-oxo-4-[(4-prop-2-ynoxyphenyl)methylidene]pyrazol-1-yl]-1,3-thiazole-5-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AN-648/41078465

XLogP
3.44632
TPSA (Topological Polar Surface Area)
81.09
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
29
Complexity
1044.8688
Exact Mass
409.10962
Monoisotopic Mass
409.10962
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AN-648/41078465

The XLogP value of 3.44632 indicates that AN-648/41078465 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.09 Ų falls within the moderate polarity range, balancing permeability and solubility for AN-648/41078465. Following Lipinski's Rule of Five, AN-648/41078465 has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AN-648/41078465?

The CAS number of AN-648/41078465 is 445429-60-7.

What is the molecular formula of AN-648/41078465?

The molecular formula of AN-648/41078465 is C21H19N3O4S.

What is the molecular weight of AN-648/41078465?

The molecular weight of AN-648/41078465 is 409.11 g/mol.

Where can I buy AN-648/41078465?

You can request a quote for AN-648/41078465 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AN-648/41078465?

Yes, KEHONG BIO provides custom synthesis services for AN-648/41078465 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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