![[4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone structure](/static/products/445/445384-01-0.png)
[4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone
TL;DR: [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone (CAS 445384-01-0) is a chemical compound with molecular formula C16H12FN3OS and molecular weight 313.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone
Also Known As: AM-807/14956081, BRD-K38695315-001-05-7, [4-amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone, [4-amino-2-(2-fluoroanilino)-5-thiazolyl]-phenylmethanone, [4-amino-2-(2-fluoroanilino)thiazol-5-yl]-phenyl-methanone
| Molecular Formula | C16H12FN3OS |
|---|---|
| Molecular Weight | 313.07 g/mol |
| LogP | 3.839 |
| Topological Polar Surface Area | 68.01 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 313.0685 |
| Heavy Atoms | 22 |
| Complexity | 817.26807 |
Chemical Identifiers
| CAS Number | 445384-01-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)C2=C(N=C(S2)NC3=CC=CC=C3F)N |
Product Overview
[4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone (CAS 445384-01-0), with molecular formula C16H12FN3OS and molecular weight 313.07 g/mol. IUPAC: [4-amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone.
Chemical Property Profile of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone
Property Insights of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone
The XLogP value of 3.839 indicates that [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.01 Ų falls within the moderate polarity range, balancing permeability and solubility for [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone. Following Lipinski's Rule of Five, [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone?
The CAS number of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone is 445384-01-0.
What is the molecular formula of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone?
The molecular formula of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone is C16H12FN3OS.
What is the molecular weight of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone?
The molecular weight of [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone is 313.07 g/mol.
Where can I buy [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone?
You can request a quote for [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone?
Yes, KEHONG BIO provides custom synthesis services for [4-Amino-2-(2-fluoroanilino)-1,3-thiazol-5-yl]-phenylmethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.