SKLB730
TL;DR: SKLB730 (CAS 445267-82-3) is a chemical compound with molecular formula C22H18ClN3O2S and molecular weight 423.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-amino-N-[(4-chlorophenyl)methyl]-6-(3-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide
Also Known As: SKLB730, AM-807/13614945, 3-amino-N-[(4-chlorophenyl)methyl]-6-(3-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(4-chlorobenzyl)-6-(3-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(4-chlorobenzyl)-6-(3-methoxyphenyl)thieno(2,3-b)pyridine-2-carboxamide
| Molecular Formula | C22H18ClN3O2S |
|---|---|
| Molecular Weight | 423.08 g/mol |
| LogP | 5.1375 |
| Topological Polar Surface Area | 77.24 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 423.0808 |
| Heavy Atoms | 29 |
| Complexity | 1188.6145 |
Chemical Identifiers
| CAS Number | 445267-82-3 |
|---|---|
| SMILES | COC1=CC=CC(=C1)C2=NC3=C(C=C2)C(=C(S3)C(=O)NCC4=CC=C(C=C4)Cl)N |
Product Overview
SKLB730 (CAS 445267-82-3), with molecular formula C22H18ClN3O2S and molecular weight 423.08 g/mol. IUPAC: 3-amino-N-[(4-chlorophenyl)methyl]-6-(3-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide.
Chemical Property Profile of SKLB730
Property Insights of SKLB730
The XLogP value of 5.1375 indicates that SKLB730 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.24 Ų falls within the moderate polarity range, balancing permeability and solubility for SKLB730. Following Lipinski's Rule of Five, SKLB730 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SKLB730?
The CAS number of SKLB730 is 445267-82-3.
What is the molecular formula of SKLB730?
The molecular formula of SKLB730 is C22H18ClN3O2S.
What is the molecular weight of SKLB730?
The molecular weight of SKLB730 is 423.08 g/mol.
Where can I buy SKLB730?
You can request a quote for SKLB730 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SKLB730?
Yes, KEHONG BIO provides custom synthesis services for SKLB730 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.