2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide
TL;DR: 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide (CAS 445266-24-0) is a chemical compound with molecular formula C18H11F2N3OS2 and molecular weight 387.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(3-cyano-6-thiophen-2-yl-2-pyridinyl)sulfanyl]-N-(2,6-difluorophenyl)acetamide
Also Known As: AM-807/12740305, 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide, 2-((3-cyano-6-(thiophen-2-yl)pyridin-2-yl)thio)-N-(2,6-difluorophenyl)acetamide, 2-{[3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-(2,6-difluorophenyl)acetamide, 2-{[3-cyano-6-(thiophen-2-yl)pyridin-2-yl]sulfanyl}-N-(2,6-difluorophenyl)acetamide
| Molecular Formula | C18H11F2N3OS2 |
|---|---|
| Molecular Weight | 387.03 g/mol |
| LogP | 4.69078 |
| Topological Polar Surface Area | 65.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 387.03116 |
| Heavy Atoms | 26 |
| Complexity | 964.34644 |
Chemical Identifiers
| CAS Number | 445266-24-0 |
|---|---|
| SMILES | C1=CC(=C(C(=C1)F)NC(=O)CSC2=C(C=CC(=N2)C3=CC=CS3)C#N)F |
Product Overview
2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide (CAS 445266-24-0), with molecular formula C18H11F2N3OS2 and molecular weight 387.03 g/mol. IUPAC: 2-[(3-cyano-6-thiophen-2-yl-2-pyridinyl)sulfanyl]-N-(2,6-difluorophenyl)acetamide.
Chemical Property Profile of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide
Property Insights of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide
The XLogP value of 4.69078 indicates that 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.78 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide. Following Lipinski's Rule of Five, 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide?
The CAS number of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide is 445266-24-0.
What is the molecular formula of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide?
The molecular formula of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide is C18H11F2N3OS2.
What is the molecular weight of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide?
The molecular weight of 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide is 387.03 g/mol.
Where can I buy 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide?
You can request a quote for 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-cyano-6-thiophen-2-ylpyridin-2-yl)sulfanyl-N-(2,6-difluorophenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.