4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile structure

4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile

TL;DR: 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile (CAS 445265-82-7) is a chemical compound with molecular formula C20H16ClN3O3S and molecular weight 413.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile

Also Known As: 4-amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile, AM-807/12427313, 4-amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)-3-thiophenecarbonitrile, 4-amino-2-((3-chlorophenyl)amino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile, 4-amino-2-[(3-chlorophenyl)amino]-5-[(3,4-dimethoxyphenyl)carbonyl]thiophene-3-carbonitrile

CAS: 445265-82-7
Molecular Formula C20H16ClN3O3S
Molecular Weight 413.06 g/mol
LogP 4.84718
Topological Polar Surface Area 97.37 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 413.0601
Heavy Atoms 28
Complexity 1088.7854

Chemical Identifiers

CAS Number 445265-82-7
SMILES COC1=C(C=C(C=C1)C(=O)C2=C(C(=C(S2)NC3=CC(=CC=C3)Cl)C#N)N)OC

Product Overview

4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile (CAS 445265-82-7), with molecular formula C20H16ClN3O3S and molecular weight 413.06 g/mol. IUPAC: 4-amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile

XLogP
4.84718
TPSA (Topological Polar Surface Area)
97.37
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
28
Complexity
1088.7854
Exact Mass
413.0601
Monoisotopic Mass
413.0601
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile

The XLogP value of 4.84718 indicates that 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.37 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile. Following Lipinski's Rule of Five, 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile?

The CAS number of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile is 445265-82-7.

What is the molecular formula of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile?

The molecular formula of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile is C20H16ClN3O3S.

What is the molecular weight of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile?

The molecular weight of 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile is 413.06 g/mol.

Where can I buy 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile?

You can request a quote for 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile?

Yes, KEHONG BIO provides custom synthesis services for 4-Amino-2-(3-chloroanilino)-5-(3,4-dimethoxybenzoyl)thiophene-3-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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