AM-807/12427051 structure

AM-807/12427051

TL;DR: AM-807/12427051 (CAS 445265-59-8) is a chemical compound with molecular formula C27H31N5O4 and molecular weight 489.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 6-amino-5,7,7-tricyano-8-(3-methoxy-4-pentoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate

Also Known As: AM-807/12427051, ethyl 6-amino-5,7,7-tricyano-8-(3-methoxy-4-pentoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate, ethyl 6-amino-5,7,7-tricyano-8-(3-methoxy-4-(pentyloxy)phenyl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate, ethyl 6-amino-5,7,7-tricyano-8-[3-(methyloxy)-4-(pentyloxy)phenyl]-3,7,8,8a-tetrahydroisoquinoline-2(1H)-carboxylate, ethyl 6-amino-5,7,7-tricyano-8-[3-methoxy-4-(pentyloxy)phenyl]-3,7,8,8a-tetrahydroisoquinoline-2(1H)-carboxylate

CAS: 445265-59-8
Molecular Formula C27H31N5O4
Molecular Weight 489.24 g/mol
LogP 4.14604
Topological Polar Surface Area 145.39 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 8
Rotatable Bonds 8
Exact Mass 489.2376
Heavy Atoms 36
Complexity 1170.0151

Chemical Identifiers

CAS Number 445265-59-8
SMILES CCCCCOC1=C(C=C(C=C1)C2C3CN(CC=C3C(=C(C2(C#N)C#N)N)C#N)C(=O)OCC)OC

Product Overview

AM-807/12427051 (CAS 445265-59-8), with molecular formula C27H31N5O4 and molecular weight 489.24 g/mol. IUPAC: ethyl 6-amino-5,7,7-tricyano-8-(3-methoxy-4-pentoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AM-807/12427051

XLogP
4.14604
TPSA (Topological Polar Surface Area)
145.39
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
8
Rotatable Bonds
8
Heavy Atoms
36
Complexity
1170.0151
Exact Mass
489.2376
Monoisotopic Mass
489.2376
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AM-807/12427051

The XLogP value of 4.14604 indicates that AM-807/12427051 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 145.39 Ų indicates high polarity, suggesting AM-807/12427051 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, AM-807/12427051 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AM-807/12427051?

The CAS number of AM-807/12427051 is 445265-59-8.

What is the molecular formula of AM-807/12427051?

The molecular formula of AM-807/12427051 is C27H31N5O4.

What is the molecular weight of AM-807/12427051?

The molecular weight of AM-807/12427051 is 489.24 g/mol.

Where can I buy AM-807/12427051?

You can request a quote for AM-807/12427051 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AM-807/12427051?

Yes, KEHONG BIO provides custom synthesis services for AM-807/12427051 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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