![1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine structure](/static/products/4452/445258-70-8.webp)
1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine
TL;DR: 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine (CAS 445258-70-8) is a chemical compound with molecular formula C21H22F4N2O2 and molecular weight 410.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-phenylpiperazin-1-yl)-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone
Also Known As: 1-phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine, (4-phenylpiperazin-1-yl)-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone, 3-[(4-phenyl-1-piperazinyl)carbonyl]benzyl 2,2,3,3-tetrafluoropropyl ether, (4-phenylpiperazin-1-yl){3-[(2,2,3,3-tetrafluoropropoxy)methyl]phenyl}methanone
| Molecular Formula | C21H22F4N2O2 |
|---|---|
| Molecular Weight | 410.16 g/mol |
| LogP | 4.066 |
| Topological Polar Surface Area | 32.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 410.16174 |
| Heavy Atoms | 29 |
| Complexity | 809.3382 |
Chemical Identifiers
| CAS Number | 445258-70-8 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=O)C3=CC=CC(=C3)COCC(C(F)F)(F)F |
Product Overview
1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine (CAS 445258-70-8), with molecular formula C21H22F4N2O2 and molecular weight 410.16 g/mol. IUPAC: (4-phenylpiperazin-1-yl)-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone.
Chemical Property Profile of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine
Property Insights of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine
The XLogP value of 4.066 indicates that 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.78 Ų, 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine?
The CAS number of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine is 445258-70-8.
What is the molecular formula of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine?
The molecular formula of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine is C21H22F4N2O2.
What is the molecular weight of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine?
The molecular weight of 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine is 410.16 g/mol.
Where can I buy 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine?
You can request a quote for 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-Phenyl-4-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.