Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate structure

Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate

TL;DR: Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate (CAS 445258-47-9) is a chemical compound with molecular formula C21H18N2O5S and molecular weight 410.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 4-(3-methylphenyl)-2-[(4-nitrobenzoyl)amino]thiophene-3-carboxylate

Also Known As: ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate, ethyl 2-(4-nitrobenzamido)-4-(m-tolyl)thiophene-3-carboxylate, ethyl 4-(3-methylphenyl)-2-[(4-nitrobenzoyl)amino]thiophene-3-carboxylate, ethyl 4-(3-methylphenyl)-2-[(4-nitrophenyl)carbonylamino]thiophene-3-carboxyla te, ethyl 4-(3-methylphenyl)-2-{[(4-nitrophenyl)carbonyl]amino}thiophene-3-carboxylate

CAS: 445258-47-9
Molecular Formula C21H18N2O5S
Molecular Weight 410.09 g/mol
LogP 5.06072
Topological Polar Surface Area 98.54 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 410.09363
Heavy Atoms 29
Complexity 1072.9304

Chemical Identifiers

CAS Number 445258-47-9
SMILES CCOC(=O)C1=C(SC=C1C2=CC=CC(=C2)C)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]

Product Overview

Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate (CAS 445258-47-9), with molecular formula C21H18N2O5S and molecular weight 410.09 g/mol. IUPAC: ethyl 4-(3-methylphenyl)-2-[(4-nitrobenzoyl)amino]thiophene-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate

XLogP
5.06072
TPSA (Topological Polar Surface Area)
98.54
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
29
Complexity
1072.9304
Exact Mass
410.09363
Monoisotopic Mass
410.09363
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate

The XLogP value of 5.06072 indicates that Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.54 Ų falls within the moderate polarity range, balancing permeability and solubility for Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate. Following Lipinski's Rule of Five, Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate?

The CAS number of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate is 445258-47-9.

What is the molecular formula of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate?

The molecular formula of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate is C21H18N2O5S.

What is the molecular weight of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate?

The molecular weight of Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate is 410.09 g/mol.

Where can I buy Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate?

You can request a quote for Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 2-({4-nitrobenzoyl}amino)-4-(3-methylphenyl)-3-thiophenecarboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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