![7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4452/445245-18-1.webp)
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445245-18-1) is a chemical compound with molecular formula C26H18F2N6O4S and molecular weight 548.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[3-nitro-5-(pyridin-2-ylsulfanyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(DIFLUOROMETHYL)-5-(4-METHOXYPHENYL)-N-[3-NITRO-5-(2-PYRIDYLSULFANYL)PHENYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE, 7-(difluoromethyl)-N-[3-nitro-5-(2-pyridinylsulfanyl)phenyl]-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C26H18F2N6O4S |
|---|---|
| Molecular Weight | 548.11 g/mol |
| LogP | 6.0492 |
| Topological Polar Surface Area | 124.55 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 548.10785 |
| Heavy Atoms | 39 |
| Complexity | 1680.0221 |
Chemical Identifiers
| CAS Number | 445245-18-1 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC(=CC(=C4)SC5=CC=CC=N5)[N+](=O)[O-] |
Product Overview
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445245-18-1), with molecular formula C26H18F2N6O4S and molecular weight 548.11 g/mol. IUPAC: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 6.0492 indicates that 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 124.55 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 445245-18-1.
What is the molecular formula of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is C26H18F2N6O4S.
What is the molecular weight of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 548.11 g/mol.
Where can I buy 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(3-nitro-5-pyridin-2-ylsulfanylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.