![N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide structure](/static/products/445/445244-33-7.png)
N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide
TL;DR: N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide (CAS 445244-33-7) is a chemical compound with molecular formula C23H18ClN3O3S and molecular weight 451.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide
Also Known As: N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide, N'-[(5-chloro-2-thienyl)methylene]-2-(2,4-dimethoxyphenyl)-4-quinolinecarbohydrazide, N'-[(E)-(5-chlorothiophen-2-yl)methylidene]-2-(2,4-dimethoxyphenyl)quinoline-4-carbohydrazide, N-[(1E)-2-(5-chloro(2-thienyl))-1-azavinyl][2-(2,4-dimethoxyphenyl)(4-quinolyl )]carboxamide
| Molecular Formula | C23H18ClN3O3S |
|---|---|
| Molecular Weight | 451.08 g/mol |
| LogP | 5.3978 |
| Topological Polar Surface Area | 72.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 451.07574 |
| Heavy Atoms | 31 |
| Complexity | 1286.2982 |
Chemical Identifiers
| CAS Number | 445244-33-7 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)N/N=C/C4=CC=C(S4)Cl)OC |
Product Overview
N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide (CAS 445244-33-7), with molecular formula C23H18ClN3O3S and molecular weight 451.08 g/mol. IUPAC: N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide.
Chemical Property Profile of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide
Property Insights of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide
The XLogP value of 5.3978 indicates that N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.81 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide. Following Lipinski's Rule of Five, N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide?
The CAS number of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide is 445244-33-7.
What is the molecular formula of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide?
The molecular formula of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide is C23H18ClN3O3S.
What is the molecular weight of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide?
The molecular weight of N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide is 451.08 g/mol.
Where can I buy N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide?
You can request a quote for N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-2-(2,4-dimethoxyphenyl)quinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.