![N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4452/445238-15-3.webp)
N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445238-15-3) is a chemical compound with molecular formula C27H19Cl2F2N5O4S and molecular weight 617.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-{4-[(3,4-dichloroanilino)sulfonyl]phenyl}-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-{4-[(3,4-dichlorophenyl)sulfamoyl]phenyl}-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C27H19Cl2F2N5O4S |
|---|---|
| Molecular Weight | 617.05 g/mol |
| LogP | 6.7024 |
| Topological Polar Surface Area | 114.69 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 617.0503 |
| Heavy Atoms | 41 |
| Complexity | 1866.0066 |
Chemical Identifiers
| CAS Number | 445238-15-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC=C(C=C4)S(=O)(=O)NC5=CC(=C(C=C5)Cl)Cl |
Product Overview
N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445238-15-3), with molecular formula C27H19Cl2F2N5O4S and molecular weight 617.05 g/mol. IUPAC: N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 6.7024 indicates that N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.69 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 445238-15-3.
What is the molecular formula of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is C27H19Cl2F2N5O4S.
What is the molecular weight of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 617.05 g/mol.
Where can I buy N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-[(3,4-dichlorophenyl)sulfamoyl]phenyl]-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.