![7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4452/445238-07-3.webp)
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445238-07-3) is a chemical compound with molecular formula C28H23F2N5O5S and molecular weight 579.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(DIFLUOROMETHYL)-N-{4-[(2-METHOXYANILINO)SULFONYL]PHENYL}-5-(4-METHOXYPHENYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE
| Molecular Formula | C28H23F2N5O5S |
|---|---|
| Molecular Weight | 579.14 g/mol |
| LogP | 5.4042 |
| Topological Polar Surface Area | 123.92 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 579.1388 |
| Heavy Atoms | 41 |
| Complexity | 1825.7966 |
Chemical Identifiers
| CAS Number | 445238-07-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC=C(C=C4)S(=O)(=O)NC5=CC=CC=C5OC |
Product Overview
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445238-07-3), with molecular formula C28H23F2N5O5S and molecular weight 579.14 g/mol. IUPAC: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 5.4042 indicates that 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 123.92 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is 445238-07-3.
What is the molecular formula of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is C28H23F2N5O5S.
What is the molecular weight of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is 579.14 g/mol.
Where can I buy 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-[(2-methoxyphenyl)sulfamoyl]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.