![7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4452/445230-95-5.webp)
7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445230-95-5) is a chemical compound with molecular formula C21H15F2IN4O and molecular weight 504.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C21H15F2IN4O |
|---|---|
| Molecular Weight | 504.03 g/mol |
| LogP | 5.49922 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 504.02588 |
| Heavy Atoms | 29 |
| Complexity | 1205.2633 |
Chemical Identifiers
| CAS Number | 445230-95-5 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC(=CC=C4)I |
Product Overview
7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445230-95-5), with molecular formula C21H15F2IN4O and molecular weight 504.03 g/mol. IUPAC: 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 5.49922 indicates that 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 445230-95-5.
What is the molecular formula of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is C21H15F2IN4O.
What is the molecular weight of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 504.03 g/mol.
Where can I buy 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 7-(difluoromethyl)-N-(3-iodophenyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.