VU0047981-1 structure

VU0047981-1

TL;DR: VU0047981-1 (CAS 445230-14-8) is a chemical compound with molecular formula C23H17F2N5O and molecular weight 417.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(2-methylbenzimidazol-1-yl)methanone

Also Known As: VU0047981-1, [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(2-methylbenzimidazol-1-yl)methanone, 7-(difluoromethyl)-3-[(2-methyl-1H-benzimidazol-1-yl)carbonyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine, [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl](2-methyl-1H-benzimidazol-1-yl)methanone, 1-[7-(DIFLUOROMETHYL)-5-(4-METHYLPHENYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONYL]-2-METHYL-1H-1,3-BENZODIAZOLE

CAS: 445230-14-8
Molecular Formula C23H17F2N5O
Molecular Weight 417.14 g/mol
LogP 4.98894
Topological Polar Surface Area 65.08 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 417.1401
Heavy Atoms 31
Complexity 1450.6796

Chemical Identifiers

CAS Number 445230-14-8
SMILES CC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)N4C(=NC5=CC=CC=C54)C

Product Overview

VU0047981-1 (CAS 445230-14-8), with molecular formula C23H17F2N5O and molecular weight 417.14 g/mol. IUPAC: [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(2-methylbenzimidazol-1-yl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of VU0047981-1

XLogP
4.98894
TPSA (Topological Polar Surface Area)
65.08
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
31
Complexity
1450.6796
Exact Mass
417.1401
Monoisotopic Mass
417.1401
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of VU0047981-1

The XLogP value of 4.98894 indicates that VU0047981-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.08 Ų falls within the moderate polarity range, balancing permeability and solubility for VU0047981-1. Following Lipinski's Rule of Five, VU0047981-1 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of VU0047981-1?

The CAS number of VU0047981-1 is 445230-14-8.

What is the molecular formula of VU0047981-1?

The molecular formula of VU0047981-1 is C23H17F2N5O.

What is the molecular weight of VU0047981-1?

The molecular weight of VU0047981-1 is 417.14 g/mol.

Where can I buy VU0047981-1?

You can request a quote for VU0047981-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for VU0047981-1?

Yes, KEHONG BIO provides custom synthesis services for VU0047981-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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