1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine
TL;DR: 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine (CAS 445227-74-7) is a chemical compound with molecular formula C22H27FN2O2S and molecular weight 402.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-cyclohexylphenyl)sulfonyl-4-(4-fluorophenyl)piperazine
Also Known As: 1-(4-cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine, 1-((4-cyclohexylphenyl)sulfonyl)-4-(4-fluorophenyl)piperazine, 1-(4-cyclohexylphenyl)sulfonyl-4-(4-fluorophenyl)piperazine, 1-[(4-cyclohexylphenyl)sulfonyl]-4-(4-fluorophenyl)piperazine, F1249-0079
| Molecular Formula | C22H27FN2O2S |
|---|---|
| Molecular Weight | 402.18 g/mol |
| LogP | 4.3843 |
| Topological Polar Surface Area | 40.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 402.17773 |
| Heavy Atoms | 28 |
| Complexity | 883.1389 |
Chemical Identifiers
| CAS Number | 445227-74-7 |
|---|---|
| SMILES | C1CCC(CC1)C2=CC=C(C=C2)S(=O)(=O)N3CCN(CC3)C4=CC=C(C=C4)F |
Product Overview
1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine (CAS 445227-74-7), with molecular formula C22H27FN2O2S and molecular weight 402.18 g/mol. IUPAC: 1-(4-cyclohexylphenyl)sulfonyl-4-(4-fluorophenyl)piperazine.
Chemical Property Profile of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine
Property Insights of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine
The XLogP value of 4.3843 indicates that 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.62 Ų, 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine?
The CAS number of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine is 445227-74-7.
What is the molecular formula of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine?
The molecular formula of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine is C22H27FN2O2S.
What is the molecular weight of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine?
The molecular weight of 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine is 402.18 g/mol.
Where can I buy 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine?
You can request a quote for 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-Cyclohexylbenzenesulfonyl)-4-(4-fluorophenyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.