MuRF1-IN-1 structure

MuRF1-IN-1

TL;DR: MuRF1-IN-1 (CAS 445222-91-3) is a chemical compound with molecular formula C18H15N3O3 and molecular weight 321.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-amino-1'-methyl-2',5-dioxospiro[7,8-dihydro-6H-chromene-4,3'-indole]-3-carbonitrile

Also Known As: MuRF1-IN-1, EMBL, EMBL?, EX-A7563, 2-Amino-1'-methyl-2',5-dioxo-5,6,7,8-tetrahydrospiro[chromene-4,3'-indoline]-3-carbonitrile

CAS: 445222-91-3
Molecular Formula C18H15N3O3
Molecular Weight 321.11 g/mol
LogP 1.63198
Topological Polar Surface Area 96.42 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 0
Exact Mass 321.11133
Heavy Atoms 24
Complexity 906.3292

Chemical Identifiers

CAS Number 445222-91-3
SMILES CN1C2=CC=CC=C2C3(C1=O)C(=C(OC4=C3C(=O)CCC4)N)C#N

Product Overview

MuRF1-IN-1 (CAS 445222-91-3), with molecular formula C18H15N3O3 and molecular weight 321.11 g/mol. IUPAC: 2-amino-1'-methyl-2',5-dioxospiro[7,8-dihydro-6H-chromene-4,3'-indole]-3-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of MuRF1-IN-1

XLogP
1.63198
TPSA (Topological Polar Surface Area)
96.42
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
0
Heavy Atoms
24
Complexity
906.3292
Exact Mass
321.11133
Monoisotopic Mass
321.11133
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of MuRF1-IN-1

The XLogP value of 1.63198 suggests moderate lipophilicity, balancing water solubility and membrane permeability for MuRF1-IN-1. The TPSA of 96.42 Ų falls within the moderate polarity range, balancing permeability and solubility for MuRF1-IN-1. Following Lipinski's Rule of Five, MuRF1-IN-1 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of MuRF1-IN-1?

The CAS number of MuRF1-IN-1 is 445222-91-3.

What is the molecular formula of MuRF1-IN-1?

The molecular formula of MuRF1-IN-1 is C18H15N3O3.

What is the molecular weight of MuRF1-IN-1?

The molecular weight of MuRF1-IN-1 is 321.11 g/mol.

Where can I buy MuRF1-IN-1?

You can request a quote for MuRF1-IN-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for MuRF1-IN-1?

Yes, KEHONG BIO provides custom synthesis services for MuRF1-IN-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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