![7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4450/445036-72-6.webp)
7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445036-72-6) is a chemical compound with molecular formula C20H13F2IN4O and molecular weight 490.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C20H13F2IN4O |
|---|---|
| Molecular Weight | 490.01 g/mol |
| LogP | 5.1908 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 490.01022 |
| Heavy Atoms | 28 |
| Complexity | 1161.5594 |
Chemical Identifiers
| CAS Number | 445036-72-6 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC(=CC=C4)I |
Product Overview
7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 445036-72-6), with molecular formula C20H13F2IN4O and molecular weight 490.01 g/mol. IUPAC: 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 5.1908 indicates that 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide is 445036-72-6.
What is the molecular formula of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide is C20H13F2IN4O.
What is the molecular weight of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide is 490.01 g/mol.
Where can I buy 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 7-(difluoromethyl)-N-(3-iodophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.