N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide
TL;DR: N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide (CAS 445024-82-8) is a chemical compound with molecular formula C26H25N3O2S and molecular weight 443.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide
Also Known As: N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide, N-[3-(aminocarbonyl)-5-isopropyl-2-thienyl]-2-(3,4-dimethylphenyl)-4-quinolinecarboxamide, N-[3-carbamoyl-5-(propan-2-yl)thiophen-2-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide, 2-{[2-(3,4-dimethylphenyl)(4-quinolyl)]carbonylamino}-5-(methylethyl)thiophene -3-carboxamide
| Molecular Formula | C26H25N3O2S |
|---|---|
| Molecular Weight | 443.17 g/mol |
| LogP | 6.05474 |
| Topological Polar Surface Area | 85.08 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 443.16675 |
| Heavy Atoms | 32 |
| Complexity | 1354.6984 |
Chemical Identifiers
| CAS Number | 445024-82-8 |
|---|---|
| SMILES | CC1=C(C=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)NC4=C(C=C(S4)C(C)C)C(=O)N)C |
Product Overview
N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide (CAS 445024-82-8), with molecular formula C26H25N3O2S and molecular weight 443.17 g/mol. IUPAC: N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide.
Chemical Property Profile of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide
Property Insights of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide
The XLogP value of 6.05474 indicates that N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.08 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide. Following Lipinski's Rule of Five, N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide?
The CAS number of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide is 445024-82-8.
What is the molecular formula of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide?
The molecular formula of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide is C26H25N3O2S.
What is the molecular weight of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide?
The molecular weight of N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide is 443.17 g/mol.
Where can I buy N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide?
You can request a quote for N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-carbamoyl-5-propan-2-ylthiophen-2-yl)-2-(3,4-dimethylphenyl)quinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.