N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide structure

N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide

TL;DR: N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide (CAS 445022-35-5) is a chemical compound with molecular formula C25H18N4O5 and molecular weight 454.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(2-methylphenyl)-N-[(E)-(6-nitro-1,3-benzodioxol-5-yl)methylideneamino]quinoline-4-carboxamide

Also Known As: N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide, 2-(2-methylphenyl)-N-[(E)-(6-nitro-1,3-benzodioxol-5-yl)methylideneamino]quinoline-4-carboxamide, 2-(2-methylphenyl)-N'-[(E)-(6-nitro-1,3-benzodioxol-5-yl)methylidene]quinoline-4-carbohydrazide, N-[(1E)-2-(6-nitro(2H-benzo[3,4-d]1,3-dioxolan-5-yl))-1-azavinyl][2-(2-methylp henyl)(4-quinolyl)]carboxamide

CAS: 445022-35-5
Molecular Formula C25H18N4O5
Molecular Weight 454.13 g/mol
LogP 4.61102
Topological Polar Surface Area 115.95 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 454.12772
Heavy Atoms 34
Complexity 1481.903

Chemical Identifiers

CAS Number 445022-35-5
SMILES CC1=CC=CC=C1C2=NC3=CC=CC=C3C(=C2)C(=O)N/N=C/C4=CC5=C(C=C4[N+](=O)[O-])OCO5

Product Overview

N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide (CAS 445022-35-5), with molecular formula C25H18N4O5 and molecular weight 454.13 g/mol. IUPAC: 2-(2-methylphenyl)-N-[(E)-(6-nitro-1,3-benzodioxol-5-yl)methylideneamino]quinoline-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide

XLogP
4.61102
TPSA (Topological Polar Surface Area)
115.95
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
34
Complexity
1481.903
Exact Mass
454.12772
Monoisotopic Mass
454.12772
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide

The XLogP value of 4.61102 indicates that N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 115.95 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide. Following Lipinski's Rule of Five, N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide?

The CAS number of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide is 445022-35-5.

What is the molecular formula of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide?

The molecular formula of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide is C25H18N4O5.

What is the molecular weight of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide?

The molecular weight of N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide is 454.13 g/mol.

Where can I buy N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide?

You can request a quote for N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for N'-({6-nitro-1,3-benzodioxol-5-yl}methylene)-2-(2-methylphenyl)-4-quinolinecarbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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