![propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate structure](/static/products/4450/445018-21-3.webp)
propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate
TL;DR: propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate (CAS 445018-21-3) is a chemical compound with molecular formula C22H22N4O4S and molecular weight 438.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate
Also Known As: propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate, isopropyl 4-methyl-2-[(2-pyrazinylcarbonyl)amino]-5-(2-toluidinocarbonyl)-3-thiophenecarboxylate, methylethyl 4-methyl-5-[N-(2-methylphenyl)carbamoyl]-2-(pyrazin-2-ylcarbonylam ino)thiophene-3-carboxylate, PROPAN-2-YL 4-METHYL-5-[(2-METHYLPHENYL)CARBAMOYL]-2-(PYRAZINE-2-AMIDO)THIOPHENE-3-CARBOXYLATE, propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-[(pyrazin-2-ylcarbonyl)amino]thiophene-3-carboxylate
| Molecular Formula | C22H22N4O4S |
|---|---|
| Molecular Weight | 438.14 g/mol |
| LogP | 4.22474 |
| Topological Polar Surface Area | 110.28 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 438.13617 |
| Heavy Atoms | 31 |
| Complexity | 1125.7946 |
Chemical Identifiers
| CAS Number | 445018-21-3 |
|---|---|
| SMILES | CC1=CC=CC=C1NC(=O)C2=C(C(=C(S2)NC(=O)C3=NC=CN=C3)C(=O)OC(C)C)C |
Product Overview
propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate (CAS 445018-21-3), with molecular formula C22H22N4O4S and molecular weight 438.14 g/mol. IUPAC: propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate.
Chemical Property Profile of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate
Property Insights of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate
The XLogP value of 4.22474 indicates that propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.28 Ų falls within the moderate polarity range, balancing permeability and solubility for propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate. Following Lipinski's Rule of Five, propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate?
The CAS number of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate is 445018-21-3.
What is the molecular formula of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate?
The molecular formula of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate is C22H22N4O4S.
What is the molecular weight of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate?
The molecular weight of propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate is 438.14 g/mol.
Where can I buy propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate?
You can request a quote for propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for propan-2-yl 4-methyl-5-[(2-methylphenyl)carbamoyl]-2-(pyrazine-2-carbonylamino)thiophene-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.