N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide
TL;DR: N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide (CAS 445008-14-0) is a chemical compound with molecular formula C13H10ClFN2OS and molecular weight 296.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-3-methylthiophene-2-carboxamide
Also Known As: N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide, N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-3-methylthiophene-2-carboxamide, N'-[(E)-(2-chloro-6-fluorophenyl)methylidene]-3-methylthiophene-2-carbohydrazide, N-[(1E)-2-(2-chloro-6-fluorophenyl)-1-azavinyl](3-methyl(2-thienyl))carboxamid e
| Molecular Formula | C13H10ClFN2OS |
|---|---|
| Molecular Weight | 296.02 g/mol |
| LogP | 3.61292 |
| Topological Polar Surface Area | 41.46 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 296.01865 |
| Heavy Atoms | 19 |
| Complexity | 619.0735 |
Chemical Identifiers
| CAS Number | 445008-14-0 |
|---|---|
| SMILES | CC1=C(SC=C1)C(=O)N/N=C/C2=C(C=CC=C2Cl)F |
Product Overview
N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide (CAS 445008-14-0), with molecular formula C13H10ClFN2OS and molecular weight 296.02 g/mol. IUPAC: N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-3-methylthiophene-2-carboxamide.
Chemical Property Profile of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide
Property Insights of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide
The XLogP value of 3.61292 indicates that N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.46 Ų, N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide?
The CAS number of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide is 445008-14-0.
What is the molecular formula of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide?
The molecular formula of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide is C13H10ClFN2OS.
What is the molecular weight of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide?
The molecular weight of N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide is 296.02 g/mol.
Where can I buy N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide?
You can request a quote for N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-(2-chloro-6-fluorobenzylidene)-3-methyl-2-thiophenecarbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.