Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate structure

Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate

TL;DR: Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate (CAS 445-71-6) is a chemical compound with molecular formula C11H9F3N2O2 and molecular weight 258.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 5-cyano-6-methyl-2-(trifluoromethyl)pyridine-3-carboxylate

Also Known As: ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate, ethyl 5-cyano-6-methyl-2-(trifluoromethyl)pyridine-3-carboxylate, 3793AE, Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)-nicotinate, ethyl5-cyano-6-methyl-2-(trifluoromethyl)nicotinate

CAS: 445-71-6
Molecular Formula C11H9F3N2O2
Molecular Weight 258.06 g/mol
LogP 2.4572
Topological Polar Surface Area 62.98 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 258.0616
Heavy Atoms 18
Complexity 518.24524

Chemical Identifiers

CAS Number 445-71-6
SMILES CCOC(=O)C1=C(N=C(C(=C1)C#N)C)C(F)(F)F

Product Overview

Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate (CAS 445-71-6), with molecular formula C11H9F3N2O2 and molecular weight 258.06 g/mol. IUPAC: ethyl 5-cyano-6-methyl-2-(trifluoromethyl)pyridine-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate

XLogP
2.4572
TPSA (Topological Polar Surface Area)
62.98
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
18
Complexity
518.24524
Exact Mass
258.0616
Monoisotopic Mass
258.0616
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate

The XLogP value of 2.4572 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate. The TPSA of 62.98 Ų falls within the moderate polarity range, balancing permeability and solubility for Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate. Following Lipinski's Rule of Five, Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate?

The CAS number of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate is 445-71-6.

What is the molecular formula of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate?

The molecular formula of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate is C11H9F3N2O2.

What is the molecular weight of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate?

The molecular weight of Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate is 258.06 g/mol.

Where can I buy Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate?

You can request a quote for Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 5-cyano-6-methyl-2-(trifluoromethyl)nicotinate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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