1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide
TL;DR: 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide (CAS 444933-34-0) is a chemical compound with molecular formula C19H20ClFN4O and molecular weight 374.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2-chloro-4-fluorophenyl)methyl]-N-[(E)-pyridin-3-ylmethylideneamino]piperidine-4-carboxamide
Also Known As: 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide, 1-(2-chloro-4-fluorobenzyl)-N'-[(E)-pyridin-3-ylmethylidene]piperidine-4-carbohydrazide, 1-[(2-chloro-4-fluoro-phenyl)methyl]-N-(pyridin-3-ylmethylideneamino)piperidine-4-carboxamide, 1-[(2-chloro-4-fluorophenyl)methyl]-N-[(E)-pyridin-3-ylmethylideneamino]piperidine-4-carboxamide, N-((1E)-2-(3-pyridyl)-1-azavinyl){1-[(2-chloro-4-fluorophenyl)methyl](4-piperi dyl)}carboxamide
| Molecular Formula | C19H20ClFN4O |
|---|---|
| Molecular Weight | 374.13 g/mol |
| LogP | 3.2364 |
| Topological Polar Surface Area | 57.59 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 374.13098 |
| Heavy Atoms | 26 |
| Complexity | 776.3635 |
Chemical Identifiers
| CAS Number | 444933-34-0 |
|---|---|
| SMILES | C1CN(CCC1C(=O)N/N=C/C2=CN=CC=C2)CC3=C(C=C(C=C3)F)Cl |
Product Overview
1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide (CAS 444933-34-0), with molecular formula C19H20ClFN4O and molecular weight 374.13 g/mol. IUPAC: 1-[(2-chloro-4-fluorophenyl)methyl]-N-[(E)-pyridin-3-ylmethylideneamino]piperidine-4-carboxamide.
Chemical Property Profile of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide
Property Insights of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide
The XLogP value of 3.2364 indicates that 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.59 Ų, 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide?
The CAS number of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide is 444933-34-0.
What is the molecular formula of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide?
The molecular formula of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide is C19H20ClFN4O.
What is the molecular weight of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide?
The molecular weight of 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide is 374.13 g/mol.
Where can I buy 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide?
You can request a quote for 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-chloro-4-fluorobenzyl)-N'-(3-pyridinylmethylene)-4-piperidinecarbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.