![1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea structure](/static/products/4449/444927-52-0.webp)
1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea
TL;DR: 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea (CAS 444927-52-0) is a chemical compound with molecular formula C21H24ClFN4O2 and molecular weight 418.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea
Also Known As: 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea, 2-{[1-(2-chloro-4-fluorobenzyl)-4-piperidinyl]carbonyl}-N-(4-methylphenyl)hydrazinecarboxamide, {1-[(2-chloro-4-fluorophenyl)methyl](4-piperidyl)}-N-{[N-(4-methylphenyl)carba moyl]amino}carboxamide, 1-[[1-[(2-chloro-4-fluoro-phenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea, 2-{[1-(2-chloro-4-fluorobenzyl)piperidin-4-yl]carbonyl}-N-(4-methylphenyl)hydrazinecarboxamide
| Molecular Formula | C21H24ClFN4O2 |
|---|---|
| Molecular Weight | 418.16 g/mol |
| LogP | 3.85242 |
| Topological Polar Surface Area | 73.47 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 418.1572 |
| Heavy Atoms | 29 |
| Complexity | 867.48486 |
Chemical Identifiers
| CAS Number | 444927-52-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)NC(=O)NNC(=O)C2CCN(CC2)CC3=C(C=C(C=C3)F)Cl |
Product Overview
1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea (CAS 444927-52-0), with molecular formula C21H24ClFN4O2 and molecular weight 418.16 g/mol. IUPAC: 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea.
Chemical Property Profile of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea
Property Insights of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea
The XLogP value of 3.85242 indicates that 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.47 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea. Following Lipinski's Rule of Five, 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea?
The CAS number of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea is 444927-52-0.
What is the molecular formula of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea?
The molecular formula of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea is C21H24ClFN4O2.
What is the molecular weight of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea?
The molecular weight of 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea is 418.16 g/mol.
Where can I buy 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea?
You can request a quote for 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea?
Yes, KEHONG BIO provides custom synthesis services for 1-[[1-[(2-chloro-4-fluorophenyl)methyl]piperidine-4-carbonyl]amino]-3-(4-methylphenyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.