N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
TL;DR: N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide (CAS 444923-30-2) is a chemical compound with molecular formula C19H15N3O3S and molecular weight 365.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-methylphenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enamide
Also Known As: N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide, (E)-3-(4-methylphenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enamide, (2E)-3-(4-methylphenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enamide, (E)-3-(4-METHYLPHENYL)-N-[4-(3-NITROPHENYL)-1,3-THIAZOL-2-YL]-2-PROPENAMIDE
| Molecular Formula | C19H15N3O3S |
|---|---|
| Molecular Weight | 365.08 g/mol |
| LogP | 4.67862 |
| Topological Polar Surface Area | 85.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 365.0834 |
| Heavy Atoms | 26 |
| Complexity | 977.7042 |
Chemical Identifiers
| CAS Number | 444923-30-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C=C/C(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-] |
Product Overview
N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide (CAS 444923-30-2), with molecular formula C19H15N3O3S and molecular weight 365.08 g/mol. IUPAC: (E)-3-(4-methylphenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enamide.
Chemical Property Profile of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
Property Insights of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
The XLogP value of 4.67862 indicates that N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.13 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide. Following Lipinski's Rule of Five, N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The CAS number of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is 444923-30-2.
What is the molecular formula of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The molecular formula of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is C19H15N3O3S.
What is the molecular weight of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The molecular weight of N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is 365.08 g/mol.
Where can I buy N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
You can request a quote for N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-{3-nitrophenyl}-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.