2-Amino-5,6-dichloro-3,4-dihydroquinazoline
TL;DR: 2-Amino-5,6-dichloro-3,4-dihydroquinazoline (CAS 444904-63-6) is a chemical compound with molecular formula C8H7Cl2N3 and molecular weight 215.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,6-dichloro-1,4-dihydroquinazolin-2-amine
Also Known As: Anagrelide impurity 5, 2-Amino-5,6-dichloro-3,4-dihydroquinazoline, 5,6-dichloro-1,4-dihydroquinazolin-2-amine, Anagrelide Impurity 26, Anagrelide Impurity 27
| Molecular Formula | C8H7Cl2N3 |
|---|---|
| Molecular Weight | 215.00 g/mol |
| LogP | 2.2336 |
| Topological Polar Surface Area | 50.41 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 215.00171 |
| Heavy Atoms | 13 |
| Complexity | 387.22067 |
Chemical Identifiers
| CAS Number | 444904-63-6 |
|---|---|
| SMILES | C1C2=C(C=CC(=C2Cl)Cl)NC(=N1)N |
Product Overview
2-Amino-5,6-dichloro-3,4-dihydroquinazoline (CAS 444904-63-6), with molecular formula C8H7Cl2N3 and molecular weight 215.00 g/mol. IUPAC: 5,6-dichloro-1,4-dihydroquinazolin-2-amine.
Chemical Property Profile of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline
Property Insights of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline
The XLogP value of 2.2336 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Amino-5,6-dichloro-3,4-dihydroquinazoline. With a topological polar surface area (TPSA) of 50.41 Ų, 2-Amino-5,6-dichloro-3,4-dihydroquinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Amino-5,6-dichloro-3,4-dihydroquinazoline has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline?
The CAS number of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline is 444904-63-6.
What is the molecular formula of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline?
The molecular formula of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline is C8H7Cl2N3.
What is the molecular weight of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline?
The molecular weight of 2-Amino-5,6-dichloro-3,4-dihydroquinazoline is 215.00 g/mol.
Where can I buy 2-Amino-5,6-dichloro-3,4-dihydroquinazoline?
You can request a quote for 2-Amino-5,6-dichloro-3,4-dihydroquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Amino-5,6-dichloro-3,4-dihydroquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 2-Amino-5,6-dichloro-3,4-dihydroquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.