AH-487/41183592
TL;DR: AH-487/41183592 (CAS 444784-36-5) is a chemical compound with molecular formula C22H21ClFNO4S and molecular weight 449.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[[3-chloro-5-ethoxy-4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-3-propan-2-yl-1,3-thiazolidine-2,4-dione
Also Known As: AH-487/41183592, (5E)-5-[[3-chloro-5-ethoxy-4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-3-propan-2-yl-1,3-thiazolidine-2,4-dione, (5E)-5-{3-chloro-5-ethoxy-4-[(2-fluorobenzyl)oxy]benzylidene}-3-(propan-2-yl)-1,3-thiazolidine-2,4-dione, 5-{3-chloro-5-ethoxy-4-[(2-fluorobenzyl)oxy]benzylidene}-3-isopropyl-1,3-thiazolidine-2,4-dione
| Molecular Formula | C22H21ClFNO4S |
|---|---|
| Molecular Weight | 449.09 g/mol |
| LogP | 5.9015 |
| Topological Polar Surface Area | 55.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 449.0864 |
| Heavy Atoms | 30 |
| Complexity | 1008.6272 |
Chemical Identifiers
| CAS Number | 444784-36-5 |
|---|---|
| SMILES | CCOC1=C(C(=CC(=C1)/C=C/2\C(=O)N(C(=O)S2)C(C)C)Cl)OCC3=CC=CC=C3F |
Product Overview
AH-487/41183592 (CAS 444784-36-5), with molecular formula C22H21ClFNO4S and molecular weight 449.09 g/mol. IUPAC: (5E)-5-[[3-chloro-5-ethoxy-4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-3-propan-2-yl-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of AH-487/41183592
Property Insights of AH-487/41183592
The XLogP value of 5.9015 indicates that AH-487/41183592 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.84 Ų, AH-487/41183592 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AH-487/41183592 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AH-487/41183592?
The CAS number of AH-487/41183592 is 444784-36-5.
What is the molecular formula of AH-487/41183592?
The molecular formula of AH-487/41183592 is C22H21ClFNO4S.
What is the molecular weight of AH-487/41183592?
The molecular weight of AH-487/41183592 is 449.09 g/mol.
Where can I buy AH-487/41183592?
You can request a quote for AH-487/41183592 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AH-487/41183592?
Yes, KEHONG BIO provides custom synthesis services for AH-487/41183592 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.