AH-487/41142352
TL;DR: AH-487/41142352 (CAS 444782-00-7) is a chemical compound with molecular formula C22H20FN3O3S and molecular weight 425.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(3-fluorophenyl)methylidene]-3-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,3-thiazolidine-2,4-dione
Also Known As: AH-487/41142352, (5E)-5-[(3-fluorophenyl)methylidene]-3-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,3-thiazolidine-2,4-dione, 5-(3-fluorobenzylidene)-3-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-1,3-thiazolidine-2,4-dione, (5E)-5-(3-fluorobenzylidene)-3-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,3-thiazolidine-2,4-dione
| Molecular Formula | C22H20FN3O3S |
|---|---|
| Molecular Weight | 425.12 g/mol |
| LogP | 3.2108 |
| Topological Polar Surface Area | 60.93 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 425.12094 |
| Heavy Atoms | 30 |
| Complexity | 1003.69714 |
Chemical Identifiers
| CAS Number | 444782-00-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=O)CN3C(=O)/C(=C\C4=CC(=CC=C4)F)/SC3=O |
Product Overview
AH-487/41142352 (CAS 444782-00-7), with molecular formula C22H20FN3O3S and molecular weight 425.12 g/mol. IUPAC: (5E)-5-[(3-fluorophenyl)methylidene]-3-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of AH-487/41142352
Property Insights of AH-487/41142352
The XLogP value of 3.2108 indicates that AH-487/41142352 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.93 Ų falls within the moderate polarity range, balancing permeability and solubility for AH-487/41142352. Following Lipinski's Rule of Five, AH-487/41142352 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AH-487/41142352?
The CAS number of AH-487/41142352 is 444782-00-7.
What is the molecular formula of AH-487/41142352?
The molecular formula of AH-487/41142352 is C22H20FN3O3S.
What is the molecular weight of AH-487/41142352?
The molecular weight of AH-487/41142352 is 425.12 g/mol.
Where can I buy AH-487/41142352?
You can request a quote for AH-487/41142352 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AH-487/41142352?
Yes, KEHONG BIO provides custom synthesis services for AH-487/41142352 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.