(5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one
TL;DR: (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one (CAS 444764-13-0) is a chemical compound with molecular formula C22H20Cl2N2OS and molecular weight 430.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4-dichlorophenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one, (5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4-dichlorophenyl)methylidene]-1,3-thiazol-4-one, (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)thiazol-4(5H)-one, 2-(4-benzyl-1-piperidyl)-5-[(2,4-dichlorophenyl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C22H20Cl2N2OS |
|---|---|
| Molecular Weight | 430.07 g/mol |
| LogP | 5.9184 |
| Topological Polar Surface Area | 32.67 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 430.06735 |
| Heavy Atoms | 28 |
| Complexity | 934.80786 |
Chemical Identifiers
| CAS Number | 444764-13-0 |
|---|---|
| SMILES | C1CN(CCC1CC2=CC=CC=C2)C3=NC(=O)/C(=C/C4=C(C=C(C=C4)Cl)Cl)/S3 |
Product Overview
(5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one (CAS 444764-13-0), with molecular formula C22H20Cl2N2OS and molecular weight 430.07 g/mol. IUPAC: (5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4-dichlorophenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one
Property Insights of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one
The XLogP value of 5.9184 indicates that (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.67 Ų, (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one?
The CAS number of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one is 444764-13-0.
What is the molecular formula of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one?
The molecular formula of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one is C22H20Cl2N2OS.
What is the molecular weight of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one?
The molecular weight of (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one is 430.07 g/mol.
Where can I buy (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one?
You can request a quote for (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4-dichlorobenzylidene)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.