Dopamine D4 receptor antagonist-1 structure

Dopamine D4 receptor antagonist-1

TL;DR: Dopamine D4 receptor antagonist-1 (CAS 444724-92-9) is a chemical compound with molecular formula C18H19ClN4 and molecular weight 326.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1H-benzimidazole

Also Known As: Dopamine D4 receptor antagonist-1, 2-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole, 2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1H-benzimidazole, 2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1H-benzoimidazole, 2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole

CAS: 444724-92-9
Molecular Formula C18H19ClN4
Molecular Weight 326.13 g/mol
LogP 3.5385
Topological Polar Surface Area 35.16 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 3
Exact Mass 326.12982
Heavy Atoms 23
Complexity 772.3966

Chemical Identifiers

CAS Number 444724-92-9
SMILES C1CN(CCN1CC2=NC3=CC=CC=C3N2)C4=CC(=CC=C4)Cl

Product Overview

Dopamine D4 receptor antagonist-1 (CAS 444724-92-9), with molecular formula C18H19ClN4 and molecular weight 326.13 g/mol. IUPAC: 2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1H-benzimidazole.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Dopamine D4 receptor antagonist-1

XLogP
3.5385
TPSA (Topological Polar Surface Area)
35.16
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
3
Heavy Atoms
23
Complexity
772.3966
Exact Mass
326.12982
Monoisotopic Mass
326.12982
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dopamine D4 receptor antagonist-1

The XLogP value of 3.5385 indicates that Dopamine D4 receptor antagonist-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.16 Ų, Dopamine D4 receptor antagonist-1 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dopamine D4 receptor antagonist-1 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dopamine D4 receptor antagonist-1?

The CAS number of Dopamine D4 receptor antagonist-1 is 444724-92-9.

What is the molecular formula of Dopamine D4 receptor antagonist-1?

The molecular formula of Dopamine D4 receptor antagonist-1 is C18H19ClN4.

What is the molecular weight of Dopamine D4 receptor antagonist-1?

The molecular weight of Dopamine D4 receptor antagonist-1 is 326.13 g/mol.

Where can I buy Dopamine D4 receptor antagonist-1?

You can request a quote for Dopamine D4 receptor antagonist-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dopamine D4 receptor antagonist-1?

Yes, KEHONG BIO provides custom synthesis services for Dopamine D4 receptor antagonist-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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