CHF 4227 (free base)
TL;DR: CHF 4227 (free base) (CAS 444643-64-5) is a chemical compound with molecular formula C30H33NO4 and molecular weight 471.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-methoxyphenyl)-4-[[4-(2-piperidin-1-ylethoxy)phenyl]methyl]-2H-chromen-7-ol
Also Known As: CHF 4227 (free base), BIDD:ER0112, 2H-1-Benzopyran-7-ol, 3-(4-methoxyphenyl)-4-((4-(2-(1-piperidinyl)ethoxy)phenyl)methyl)-, SID:53787480, 3-(4-methoxy)phenyl-4-((4-(2-(1-piperidinyl)ethoxy)phenyl)methyl)-2H-1-benzopyran-7-ol
| Molecular Formula | C30H33NO4 |
|---|---|
| Molecular Weight | 471.24 g/mol |
| LogP | 5.8114 |
| Topological Polar Surface Area | 51.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 471.24097 |
| Heavy Atoms | 35 |
| Complexity | 1161.9658 |
Chemical Identifiers
| CAS Number | 444643-64-5 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=C(C3=C(C=C(C=C3)O)OC2)CC4=CC=C(C=C4)OCCN5CCCCC5 |
Product Overview
CHF 4227 (free base) (CAS 444643-64-5), with molecular formula C30H33NO4 and molecular weight 471.24 g/mol. IUPAC: 3-(4-methoxyphenyl)-4-[[4-(2-piperidin-1-ylethoxy)phenyl]methyl]-2H-chromen-7-ol.
Chemical Property Profile of CHF 4227 (free base)
Property Insights of CHF 4227 (free base)
The XLogP value of 5.8114 indicates that CHF 4227 (free base) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.16 Ų, CHF 4227 (free base) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, CHF 4227 (free base) has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of CHF 4227 (free base)?
The CAS number of CHF 4227 (free base) is 444643-64-5.
What is the molecular formula of CHF 4227 (free base)?
The molecular formula of CHF 4227 (free base) is C30H33NO4.
What is the molecular weight of CHF 4227 (free base)?
The molecular weight of CHF 4227 (free base) is 471.24 g/mol.
Where can I buy CHF 4227 (free base)?
You can request a quote for CHF 4227 (free base) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for CHF 4227 (free base)?
Yes, KEHONG BIO provides custom synthesis services for CHF 4227 (free base) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.