![2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide structure](/static/products/444/444549-04-6.png)
2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide
TL;DR: 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide (CAS 444549-04-6) is a chemical compound with molecular formula C24H24N4O3 and molecular weight 416.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(4Z)-2,5-dioxo-4-[(1-propan-2-ylindol-3-yl)methylidene]imidazolidin-1-yl]-N-(4-methylphenyl)acetamide
Also Known As: 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide, (Z)-2-(4-((1-isopropyl-1H-indol-3-yl)methylene)-2,5-dioxoimidazolidin-1-yl)-N-(p-tolyl)acetamide, 2-[(4Z)-2,5-dioxo-4-[(1-propan-2-ylindol-3-yl)methylidene]imidazolidin-1-yl]-N-(4-methylphenyl)acetamide
| Molecular Formula | C24H24N4O3 |
|---|---|
| Molecular Weight | 416.18 g/mol |
| LogP | 4.06202 |
| Topological Polar Surface Area | 83.44 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 416.18484 |
| Heavy Atoms | 31 |
| Complexity | 1205.2924 |
Chemical Identifiers
| CAS Number | 444549-04-6 |
|---|---|
| SMILES | CC1=CC=C(C=C1)NC(=O)CN2C(=O)/C(=C/C3=CN(C4=CC=CC=C43)C(C)C)/NC2=O |
Product Overview
2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide (CAS 444549-04-6), with molecular formula C24H24N4O3 and molecular weight 416.18 g/mol. IUPAC: 2-[(4Z)-2,5-dioxo-4-[(1-propan-2-ylindol-3-yl)methylidene]imidazolidin-1-yl]-N-(4-methylphenyl)acetamide.
Chemical Property Profile of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide
Property Insights of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide
The XLogP value of 4.06202 indicates that 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.44 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide. Following Lipinski's Rule of Five, 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide?
The CAS number of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide is 444549-04-6.
What is the molecular formula of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide?
The molecular formula of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide is C24H24N4O3.
What is the molecular weight of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide?
The molecular weight of 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide is 416.18 g/mol.
Where can I buy 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide?
You can request a quote for 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-[(4Z)-2-hydroxy-5-oxo-4-{[1-(propan-2-yl)-1H-indol-3-yl]methylidene}-4,5-dihydro-1H-imidazol-1-yl]-N-(4-methylphenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.