10R-0268 structure

10R-0268

TL;DR: 10R-0268 (CAS 444151-76-2) is a chemical compound with molecular formula C21H22ClF3N4O3S and molecular weight 502.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[1-(benzenesulfonyl)ethyl]-3-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-4-ethyl-1H-imidazol-2-one

Also Known As: 10R-0268, 1-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)-5-ethyl-4-[1-(phenylsulfonyl)ethyl]-1,3-dihydro-2H-imidazol-2-one, 5-[1-(benzenesulfonyl)ethyl]-3-[2-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-4-ethyl-1H-imidazol-2-one, 4-[1-(benzenesulfonyl)ethyl]-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5-ethyl-2,3-dihydro-1H-imidazol-2-one

CAS: 444151-76-2
Molecular Formula C21H22ClF3N4O3S
Molecular Weight 502.11 g/mol
LogP 4.453
Topological Polar Surface Area 96.85 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 8
Exact Mass 502.10532
Heavy Atoms 33
Complexity 1288.3191

Chemical Identifiers

CAS Number 444151-76-2
SMILES CCC1=C(NC(=O)N1CCNC2=C(C=C(C=N2)C(F)(F)F)Cl)C(C)S(=O)(=O)C3=CC=CC=C3

Product Overview

10R-0268 (CAS 444151-76-2), with molecular formula C21H22ClF3N4O3S and molecular weight 502.11 g/mol. IUPAC: 5-[1-(benzenesulfonyl)ethyl]-3-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-4-ethyl-1H-imidazol-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 10R-0268

XLogP
4.453
TPSA (Topological Polar Surface Area)
96.85
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
8
Heavy Atoms
33
Complexity
1288.3191
Exact Mass
502.10532
Monoisotopic Mass
502.10532
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 10R-0268

The XLogP value of 4.453 indicates that 10R-0268 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.85 Ų falls within the moderate polarity range, balancing permeability and solubility for 10R-0268. Following Lipinski's Rule of Five, 10R-0268 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 10R-0268?

The CAS number of 10R-0268 is 444151-76-2.

What is the molecular formula of 10R-0268?

The molecular formula of 10R-0268 is C21H22ClF3N4O3S.

What is the molecular weight of 10R-0268?

The molecular weight of 10R-0268 is 502.11 g/mol.

Where can I buy 10R-0268?

You can request a quote for 10R-0268 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 10R-0268?

Yes, KEHONG BIO provides custom synthesis services for 10R-0268 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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