3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine
TL;DR: 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine (CAS 444143-45-7) is a chemical compound with molecular formula C14H9F6N and molecular weight 305.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3,5-bis(trifluoromethyl)phenyl]aniline
Also Known As: 4-Amino-3',5'-bis(trifluoromethyl)biphenyl, 3',5'-Bis(trifluoromethyl)-[1,1'-biphenyl]-4-amine, 4-[3,5-bis(trifluoromethyl)phenyl]aniline, BM208, 4-Amino-3,5-bis(trifluoromethyl)biphenyl
| Molecular Formula | C14H9F6N |
|---|---|
| Molecular Weight | 305.06 g/mol |
| LogP | 4.9734 |
| Topological Polar Surface Area | 26.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 305.0639 |
| Heavy Atoms | 21 |
| Complexity | 607.7443 |
Chemical Identifiers
| CAS Number | 444143-45-7 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)N |
Product Overview
3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine (CAS 444143-45-7), with molecular formula C14H9F6N and molecular weight 305.06 g/mol. IUPAC: 4-[3,5-bis(trifluoromethyl)phenyl]aniline.
Chemical Property Profile of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine
Property Insights of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine
The XLogP value of 4.9734 indicates that 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.02 Ų, 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine?
The CAS number of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine is 444143-45-7.
What is the molecular formula of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine?
The molecular formula of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine is C14H9F6N.
What is the molecular weight of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine?
The molecular weight of 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine is 305.06 g/mol.
Where can I buy 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine?
You can request a quote for 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine?
Yes, KEHONG BIO provides custom synthesis services for 3',5'-Bis(trifluoromethyl)(1,1'-biphenyl)-4-ylamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.