![2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one structure](/static/products/443/443963-74-4.png)
2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one
TL;DR: 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one (CAS 443963-74-4) is a chemical compound with molecular formula C24H20ClN3O2S and molecular weight 449.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenylfuran-2-yl)methylidene]-1,3-thiazol-4-one
Also Known As: 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenylfuran-2-yl)methylidene]-1,3-thiazol-4(5H)-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenylfuran-2-yl)methylidene]-1,3-thiazol-4-one, (E)-2-(4-(4-chlorophenyl)piperazin-1-yl)-5-((5-phenylfuran-2-yl)methylene)thiazol-4(5H)-one
| Molecular Formula | C24H20ClN3O2S |
|---|---|
| Molecular Weight | 449.10 g/mol |
| LogP | 5.3925 |
| Topological Polar Surface Area | 49.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 449.09647 |
| Heavy Atoms | 31 |
| Complexity | 1147.0823 |
Chemical Identifiers
| CAS Number | 443963-74-4 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)Cl)C3=NC(=O)/C(=C\C4=CC=C(O4)C5=CC=CC=C5)/S3 |
Product Overview
2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one (CAS 443963-74-4), with molecular formula C24H20ClN3O2S and molecular weight 449.10 g/mol. IUPAC: (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenylfuran-2-yl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one
Property Insights of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one
The XLogP value of 5.3925 indicates that 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.05 Ų, 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one?
The CAS number of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one is 443963-74-4.
What is the molecular formula of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one?
The molecular formula of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one is C24H20ClN3O2S.
What is the molecular weight of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one?
The molecular weight of 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one is 449.10 g/mol.
Where can I buy 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one?
You can request a quote for 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(5-phenyl-2-furyl)methylidene]-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.