3ama
TL;DR: 3ama (CAS 443883-72-5) is a chemical compound with molecular formula C15H12F2N6O3S and molecular weight 394.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino]benzenesulfonamide
Also Known As: 3ama, Aurora Kinase/Cdk Inhibitor, 4-((5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl)amino)benzenesulfonamide, 4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide, 4-[[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino]benzenesulfonamide
| Molecular Formula | C15H12F2N6O3S |
|---|---|
| Molecular Weight | 394.07 g/mol |
| LogP | 1.218 |
| Topological Polar Surface Area | 145.99 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 394.06598 |
| Heavy Atoms | 27 |
| Complexity | 1108.7041 |
Chemical Identifiers
| CAS Number | 443883-72-5 |
|---|---|
| SMILES | C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F |
Product Overview
3ama (CAS 443883-72-5), with molecular formula C15H12F2N6O3S and molecular weight 394.07 g/mol. IUPAC: 4-[[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino]benzenesulfonamide.
Chemical Property Profile of 3ama
Property Insights of 3ama
The XLogP value of 1.218 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3ama. The TPSA of 145.99 Ų indicates high polarity, suggesting 3ama may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3ama has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3ama?
The CAS number of 3ama is 443883-72-5.
What is the molecular formula of 3ama?
The molecular formula of 3ama is C15H12F2N6O3S.
What is the molecular weight of 3ama?
The molecular weight of 3ama is 394.07 g/mol.
Where can I buy 3ama?
You can request a quote for 3ama directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3ama?
Yes, KEHONG BIO provides custom synthesis services for 3ama and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.