(R)-donepezil
TL;DR: (R)-donepezil (CAS 443798-47-8) is a chemical compound with molecular formula C24H29NO3 and molecular weight 379.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Also Known As: (R)-donepezil, donepezil, (+)-donepezil, 1eve, (R)-Aricept
| Molecular Formula | C24H29NO3 |
|---|---|
| Molecular Weight | 379.21 g/mol |
| LogP | 4.3611 |
| Topological Polar Surface Area | 38.77 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 379.21475 |
| Heavy Atoms | 28 |
| Complexity | 825.24396 |
Chemical Identifiers
| CAS Number | 443798-47-8 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C[C@H](C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC |
Product Overview
(R)-donepezil (CAS 443798-47-8), with molecular formula C24H29NO3 and molecular weight 379.21 g/mol. IUPAC: (2R)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one.
Chemical Property Profile of (R)-donepezil
Property Insights of (R)-donepezil
The XLogP value of 4.3611 indicates that (R)-donepezil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.77 Ų, (R)-donepezil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (R)-donepezil has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (R)-donepezil?
The CAS number of (R)-donepezil is 443798-47-8.
What is the molecular formula of (R)-donepezil?
The molecular formula of (R)-donepezil is C24H29NO3.
What is the molecular weight of (R)-donepezil?
The molecular weight of (R)-donepezil is 379.21 g/mol.
Where can I buy (R)-donepezil?
You can request a quote for (R)-donepezil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (R)-donepezil?
Yes, KEHONG BIO provides custom synthesis services for (R)-donepezil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.