![4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione structure](/static/products/4436/443667-27-4.webp)
4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione
TL;DR: 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione (CAS 443667-27-4) is a chemical compound with molecular formula C18H15ClN2S and molecular weight 326.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-chlorophenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione
Also Known As: AB01333892-02, 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione, 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2-thiol, 4-(2-chlorophenyl)-1,3,4,5,6-pentahydrobenzo[h]quinazoline-2-thione, 4-(2-chlorophenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione
| Molecular Formula | C18H15ClN2S |
|---|---|
| Molecular Weight | 326.06 g/mol |
| LogP | 4.2163 |
| Topological Polar Surface Area | 24.06 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 326.06445 |
| Heavy Atoms | 22 |
| Complexity | 797.1791 |
Chemical Identifiers
| CAS Number | 443667-27-4 |
|---|---|
| SMILES | C1CC2=C(C3=CC=CC=C31)NC(=S)NC2C4=CC=CC=C4Cl |
Product Overview
4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione (CAS 443667-27-4), with molecular formula C18H15ClN2S and molecular weight 326.06 g/mol. IUPAC: 4-(2-chlorophenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione.
Chemical Property Profile of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione
Property Insights of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione
The XLogP value of 4.2163 indicates that 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.06 Ų, 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione?
The CAS number of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is 443667-27-4.
What is the molecular formula of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione?
The molecular formula of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is C18H15ClN2S.
What is the molecular weight of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione?
The molecular weight of 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is 326.06 g/mol.
Where can I buy 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione?
You can request a quote for 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-(2-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.