![4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine structure](/static/products/443/443642-60-2.png)
4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
TL;DR: 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 443642-60-2) is a chemical compound with molecular formula C12H16N4O5 and molecular weight 296.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,5-bis(hydroxymethyl)oxolane-3,4-diol
Also Known As: 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine, 7-[2-C-(Hydroxymethyl)-, A-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-[2-C-(Hydroxymethyl)-, A-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
| Molecular Formula | C12H16N4O5 |
|---|---|
| Molecular Weight | 296.11 g/mol |
| LogP | -2.0125 |
| Topological Polar Surface Area | 146.88 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 3 |
| Exact Mass | 296.11206 |
| Heavy Atoms | 21 |
| Complexity | 662.13525 |
Chemical Identifiers
| CAS Number | 443642-60-2 |
|---|---|
| SMILES | C1=CN(C2=NC=NC(=C21)N)[C@H]3[C@]([C@@H]([C@H](O3)CO)O)(CO)O |
Product Overview
4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 443642-60-2), with molecular formula C12H16N4O5 and molecular weight 296.11 g/mol. IUPAC: (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,5-bis(hydroxymethyl)oxolane-3,4-diol.
Chemical Property Profile of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
Property Insights of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
The XLogP value of -2.0125 indicates that 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 146.88 Ų indicates high polarity, suggesting 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine?
The CAS number of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is 443642-60-2.
What is the molecular formula of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine?
The molecular formula of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is C12H16N4O5.
What is the molecular weight of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine?
The molecular weight of 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is 296.11 g/mol.
Where can I buy 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine?
You can request a quote for 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 4-Amino-7-(2-C-hydroxymethyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.