AS-918-35a
TL;DR: AS-918-35a (CAS 443348-24-1) is a chemical compound with molecular formula C24H27ClN4O2S and molecular weight 470.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]-6-oxohexyl]-2-sulfanylidene-1H-quinazolin-4-one
Also Known As: AS-918-35a, F0916-4126, 3-[6-[4-(3-chlorophenyl)piperazin-1-yl]-6-oxohexyl]-2-sulfanylidene-1H-quinazolin-4-one, 3-{6-[4-(3-chlorophenyl)piperazin-1-yl]-6-oxohexyl}-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one, 3-(6-(4-(3-chlorophenyl)piperazin-1-yl)-6-oxohexyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
| Molecular Formula | C24H27ClN4O2S |
|---|---|
| Molecular Weight | 470.15 g/mol |
| LogP | 4.62169 |
| Topological Polar Surface Area | 61.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 470.15433 |
| Heavy Atoms | 32 |
| Complexity | 1214.3351 |
Chemical Identifiers
| CAS Number | 443348-24-1 |
|---|---|
| SMILES | C1CN(CCN1C2=CC(=CC=C2)Cl)C(=O)CCCCCN3C(=O)C4=CC=CC=C4NC3=S |
Product Overview
AS-918-35a (CAS 443348-24-1), with molecular formula C24H27ClN4O2S and molecular weight 470.15 g/mol. IUPAC: 3-[6-[4-(3-chlorophenyl)piperazin-1-yl]-6-oxohexyl]-2-sulfanylidene-1H-quinazolin-4-one.
Chemical Property Profile of AS-918-35a
Property Insights of AS-918-35a
The XLogP value of 4.62169 indicates that AS-918-35a is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.34 Ų falls within the moderate polarity range, balancing permeability and solubility for AS-918-35a. Following Lipinski's Rule of Five, AS-918-35a has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AS-918-35a?
The CAS number of AS-918-35a is 443348-24-1.
What is the molecular formula of AS-918-35a?
The molecular formula of AS-918-35a is C24H27ClN4O2S.
What is the molecular weight of AS-918-35a?
The molecular weight of AS-918-35a is 470.15 g/mol.
Where can I buy AS-918-35a?
You can request a quote for AS-918-35a directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AS-918-35a?
Yes, KEHONG BIO provides custom synthesis services for AS-918-35a and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.