4-(sec-butylamino)quinazoline-2(1H)-thione
TL;DR: 4-(sec-butylamino)quinazoline-2(1H)-thione (CAS 443348-18-3) is a chemical compound with molecular formula C12H15N3S and molecular weight 233.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(butan-2-ylamino)-1H-quinazoline-2-thione
Also Known As: 4-(sec-butylamino)quinazoline-2(1H)-thione, 4-(butan-2-ylamino)-1H-quinazoline-2-thione, 4-(sec-butylamino)-2(1H)-quinazolinethione, 4-[(butan-2-yl)amino]-1,2-dihydroquinazoline-2-thione, F0918-6890
| Molecular Formula | C12H15N3S |
|---|---|
| Molecular Weight | 233.10 g/mol |
| LogP | 3.50279 |
| Topological Polar Surface Area | 40.71 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 233.09866 |
| Heavy Atoms | 16 |
| Complexity | 547.2003 |
Chemical Identifiers
| CAS Number | 443348-18-3 |
|---|---|
| SMILES | CCC(C)NC1=NC(=S)NC2=CC=CC=C21 |
Product Overview
4-(sec-butylamino)quinazoline-2(1H)-thione (CAS 443348-18-3), with molecular formula C12H15N3S and molecular weight 233.10 g/mol. IUPAC: 4-(butan-2-ylamino)-1H-quinazoline-2-thione.
Chemical Property Profile of 4-(sec-butylamino)quinazoline-2(1H)-thione
Property Insights of 4-(sec-butylamino)quinazoline-2(1H)-thione
The XLogP value of 3.50279 indicates that 4-(sec-butylamino)quinazoline-2(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.71 Ų, 4-(sec-butylamino)quinazoline-2(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(sec-butylamino)quinazoline-2(1H)-thione has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(sec-butylamino)quinazoline-2(1H)-thione?
The CAS number of 4-(sec-butylamino)quinazoline-2(1H)-thione is 443348-18-3.
What is the molecular formula of 4-(sec-butylamino)quinazoline-2(1H)-thione?
The molecular formula of 4-(sec-butylamino)quinazoline-2(1H)-thione is C12H15N3S.
What is the molecular weight of 4-(sec-butylamino)quinazoline-2(1H)-thione?
The molecular weight of 4-(sec-butylamino)quinazoline-2(1H)-thione is 233.10 g/mol.
Where can I buy 4-(sec-butylamino)quinazoline-2(1H)-thione?
You can request a quote for 4-(sec-butylamino)quinazoline-2(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(sec-butylamino)quinazoline-2(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-(sec-butylamino)quinazoline-2(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.