Anguizole structure

Anguizole

TL;DR: Anguizole (CAS 442666-98-0) is a chemical compound with molecular formula C17H11ClF2N4O2S and molecular weight 408.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Also Known As: Anguizole, Anguizole,CAS:442666-98-0, 3447AH, 7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, W-5299

CAS: 442666-98-0
Molecular Formula C17H11ClF2N4O2S
Molecular Weight 408.03 g/mol
LogP 4.2689
Topological Polar Surface Area 72.43 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 408.02594
Heavy Atoms 27
Complexity 1088.4921

Chemical Identifiers

CAS Number 442666-98-0
SMILES C1=COC(=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)Cl)C(=O)NCC4=CC=CS4

Product Overview

Anguizole (CAS 442666-98-0), with molecular formula C17H11ClF2N4O2S and molecular weight 408.03 g/mol. IUPAC: 7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Anguizole

XLogP
4.2689
TPSA (Topological Polar Surface Area)
72.43
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
27
Complexity
1088.4921
Exact Mass
408.02594
Monoisotopic Mass
408.02594
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Anguizole

The XLogP value of 4.2689 indicates that Anguizole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.43 Ų falls within the moderate polarity range, balancing permeability and solubility for Anguizole. Following Lipinski's Rule of Five, Anguizole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Anguizole?

The CAS number of Anguizole is 442666-98-0.

What is the molecular formula of Anguizole?

The molecular formula of Anguizole is C17H11ClF2N4O2S.

What is the molecular weight of Anguizole?

The molecular weight of Anguizole is 408.03 g/mol.

Where can I buy Anguizole?

You can request a quote for Anguizole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Anguizole?

Yes, KEHONG BIO provides custom synthesis services for Anguizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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