(E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one
TL;DR: (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one (CAS 442652-91-7) is a chemical compound with molecular formula C23H25N3O3S and molecular weight 423.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-(4-benzylpiperazin-1-yl)-5-[(2,4-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one, (5E)-2-(4-benzylpiperazin-1-yl)-5-[(2,4-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one, 2-(4-benzylpiperazin-1-yl)-5-[(2,4-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C23H25N3O3S |
|---|---|
| Molecular Weight | 423.16 g/mol |
| LogP | 3.4919 |
| Topological Polar Surface Area | 54.37 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 423.16165 |
| Heavy Atoms | 30 |
| Complexity | 966.9136 |
Chemical Identifiers
| CAS Number | 442652-91-7 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)/C=C/2\C(=O)N=C(S2)N3CCN(CC3)CC4=CC=CC=C4)OC |
Product Overview
(E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one (CAS 442652-91-7), with molecular formula C23H25N3O3S and molecular weight 423.16 g/mol. IUPAC: (5E)-2-(4-benzylpiperazin-1-yl)-5-[(2,4-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one
Property Insights of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one
The XLogP value of 3.4919 indicates that (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.37 Ų, (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one?
The CAS number of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one is 442652-91-7.
What is the molecular formula of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one?
The molecular formula of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one is C23H25N3O3S.
What is the molecular weight of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one?
The molecular weight of (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one is 423.16 g/mol.
Where can I buy (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one?
You can request a quote for (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-benzylpiperazin-1-yl)-5-(2,4-dimethoxybenzylidene)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.