![3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE structure](/static/products/442/442565-79-9.png)
3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
TL;DR: 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE (CAS 442565-79-9) is a chemical compound with molecular formula C23H29N5O4S2 and molecular weight 503.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-3-(3-methoxypropyl)-5-[[9-methyl-2-(2-morpholin-4-ylethylamino)-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
Also Known As: 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, (Z)-3-(3-methoxypropyl)-5-((9-methyl-2-((2-morpholinoethyl)amino)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)-2-thioxothiazolidin-4-one, (5Z)-3-(3-METHOXYPROPYL)-5-[(9-METHYL-2-{[2-(MORPHOLIN-4-YL)ETHYL]AMINO}-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL)METHYLIDENE]-2-SULFANYLIDENE-1,3-THIAZOLIDIN-4-ONE, (5Z)-3-(3-methoxypropyl)-5-[[9-methyl-2-(2-morpholin-4-ylethylamino)-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 3-{(Z)-[3-(3-methoxypropyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}-9-methyl-2-{[2-(morpholin-4-yl)ethyl]amino}-4H-pyrido[1,2-a]pyrimidin-4-one
| Molecular Formula | C23H29N5O4S2 |
|---|---|
| Molecular Weight | 503.17 g/mol |
| LogP | 1.98472 |
| Topological Polar Surface Area | 88.41 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 9 |
| Exact Mass | 503.1661 |
| Heavy Atoms | 34 |
| Complexity | 1159.9901 |
Chemical Identifiers
| CAS Number | 442565-79-9 |
|---|---|
| SMILES | CC1=CC=CN2C1=NC(=C(C2=O)/C=C\3/C(=O)N(C(=S)S3)CCCOC)NCCN4CCOCC4 |
Product Overview
3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE (CAS 442565-79-9), with molecular formula C23H29N5O4S2 and molecular weight 503.17 g/mol. IUPAC: (5Z)-3-(3-methoxypropyl)-5-[[9-methyl-2-(2-morpholin-4-ylethylamino)-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one.
Chemical Property Profile of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
Property Insights of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
The XLogP value of 1.98472 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE. The TPSA of 88.41 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE. Following Lipinski's Rule of Five, 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The CAS number of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is 442565-79-9.
What is the molecular formula of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The molecular formula of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is C23H29N5O4S2.
What is the molecular weight of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The molecular weight of 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is 503.17 g/mol.
Where can I buy 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
You can request a quote for 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
Yes, KEHONG BIO provides custom synthesis services for 3-{(Z)-[3-(3-METHOXYPROPYL)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}-9-METHYL-2-{[2-(4-MORPHOLINYL)ETHYL]AMINO}-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.